Publications

Papers led or supervised by Dr. Gauthier (first or last author), updated automatically from Google Scholar.

2026

Physics and Morphology Constrained Quantitative Susceptibility Based Segmentation of Cerebral Veins

Yousif C. Al-Khoury, Ali Rezaei, Vanessa Raspa, Nicole Slanina, Hendrale Gresseau, Yiming Xiao, Binu P. Thomas, Claudine J. Gauthier

bioRxiv, 2026.09. 24.754280 · 01 Jan 2026

Cardiorespiratory fitness in relation to cerebral vascular and metabolic health in older adults with coronary artery disease

Safa Sanami, Stéfanie A. Tremblay, Zacharie Potvin-Jutras, Ali Rezaei, Dalia Sabra, …, Mathieu Gayda, Josep Iglesies-Grau, Anil Nigam, Louis Bherer, Claudine J. Gauthier

GeroScience, 1-17 · 01 Jan 2026

Coronary artery disease is linked with demyelination and iron deposition in white matter watershed areas

Ali Rezaei, Zacharie Potvin-Jutras, Stefanie A. Tremblay, Safa Sanami, Dalia Sabra, …, Christine L. Tardif, Josep Iglesies-Grau, Anil Nigam, Louis Bherer, Claudine J. Gauthier

bioRxiv, 2026.03. 03.709359 · 01 Jan 2026

Regional distribution of white matter hyperintensity burden in coronary artery disease and links with coronary revascularization procedure

Zacharie Potvin-Jutras, Stéfanie A. Tremblay, Ali Rezaei, Safa Sanami, Dalia Sabra, …, Christopher J. Steele, Mathieu Gayda, Anil Nigam, Louis Bherer, Claudine J. Gauthier

bioRxiv, 2026.05. 12.724587 · 01 Jan 2026

$Greater cardiorespiratory fitness is associated with higher cerebral blood flow and lower oxygen extraction fraction in healthy older adults$

Greater cardiorespiratory fitness is associated with higher cerebral blood flow and lower oxygen extraction fraction in healthy older adults

Safa Sanami, Ali Rezaei, Stéfanie A Tremblay, Zacharie Potvin-Jutras, Dalia Sabra, …, Mathieu Gayda, Josep Iglesies-Grau, Anil Nigam, Louis Bherer, Claudine J Gauthier

Journal of Cerebral Blood Flow & Metabolism 46 (6), 1559-1571 · 01 Jan 2026

Human sex-specific hormone effects on cerebrovascular health in males and females

B Intzandt, Z Potvin-Jutras, CJ Gauthier

Mechanisms of Ageing and Development, 112216 · 01 Jan 2026

2025

Links between cognition and multivariate brain white matter differences in individuals with family history of Alzheimer's disease

Stefanie A Tremblay, R. Nathan Spreng, Alfie Wearn, Zaki Alasmar, Amir Pirhadi, …, Ilana R Leppert, Felix Carbonell, Yasser Iturria Medina, Christopher J Steele, Claudine J Gauthier

Alzheimer's & Dementia 20 (Suppl 2), e090781 · 01 Jan 2025

Sex and APOE4-specific links between cardiometabolic risk factors and white matter alterations in individuals with a family history of Alzheimer's disease

Stefanie A. Tremblay, R. Nathan Spreng, Alfie Wearn, Zaki Alasmar, Amir Pirhadi, …, Ilana R. Leppert, Felix Carbonell, Yasser Iturria Medina, Christopher J. Steele, Claudine J. Gauthier

Neurobiology of Aging 150, 80-96 · 01 Jan 2025

The Impact of Coronary Artery Disease on Brain Vascular and Metabolic Health: Links to Cognitive Function

Safa Sanami, Stefanie A. Tremblay, Ali Rezaei, Zacharie Potvin-Jutras, Dalia Sabra, …, Mathieu Gayda, Josep Iglesies-Grau, Anil Nigam, Louis Bherer, Claudine J. Gauthier

bioRxiv, 2025.06. 02.657532 · 01 Jan 2025

Sex-specific effects of intensity and dose of physical activity on BOLD-fMRI cerebrovascular reactivity and cerebral pulsatility

Z Potvin-Jutras, B Intzandt, H Mohammadi, P Liu, JJ Chen, CJ Gauthier

Journal of Cerebral Blood Flow & Metabolism 45 (8), 1543-1557 · 01 Jan 2025

Preservation of cerebral vascular and metabolic health with greater cardiorespiratory fitness in coronary artery disease

Safa Sanami, Stefanie A. Tremblay, Zacharie Potvin-Jutras, Ali Rezaei, Dalia Sabra, …, Mathieu Gayda, Josep Iglesies-Grau, Anil Nigam, Louis Bherer, Claudine J. Gauthier

bioRxiv, 2025.08. 22.671781 · 01 Jan 2025

Multivariate white matter microstructure alterations in older adults with coronary artery disease

Stefanie A. Tremblay, Zacharie Potvin-Jutras, Dalia Sabra, Ali Rezaei, Safa Sanami, …, Christopher J. Steele, Josep Iglesies-Grau, Anil Nigam, Louis Bherer, Claudine J. Gauthier

The Journal of Neuroscience 45 (39), e0790252025 · 01 Jan 2025

Sex matters: the effect of physical activity on brain perfusion

B Intzandt, S Sanami, J Huck, L Bherer, CJ Gauthier

The Journals of Gerontology, Series A: Biological Sciences and Medical … · 01 Jan 2025

Reduced cerebrovascular reactivity is more pronounced in female than male youth with complex congenital heart defects

CJ Gauthier, Z Potvin-Jutras, S Sanami, K Easson, G Gilbert

[no publisher info] · 01 Jan 2025

Reduced cerebrovascular reactivity in youth with complex congenital heart defects

CJ Gauthier, Z Potvin-Jutras, S Sanami, K Easson, G Gilbert

bioRxiv, 2025.11. 03.686431 · 01 Jan 2025

Sex Hormones and Cerebrovascular Health: Implications for Dementia Risk Across the Lifespan

B Intzandt, Z Potvin‐Jutras, K Whittingstall, CJ Gauthier

Alzheimer's & Dementia 21, e104819 · 01 Jan 2025

Alzheimer's Imaging Consortium

B Intzandt, Z Potvin-Jutras, K Whittingstall, CJ Gauthier

Alzheimer's & dementia: the journal of the Alzheimer's Association 21, e109774 · 01 Jan 2025

2023

Sex-specific relationships between obesity, physical activity, and gray and white matter volume in cognitively unimpaired older adults

B Intzandt, S Sanami, J Huck, S Villeneuve, L Bherer, CJ Gauthier

GeroScience 45 (3), 1869-1888 · 01 Jan 2023

Modeling venous bias in resting state functional MRI metrics

Julia Huck, Anna‐Thekla Jäger, Uta Schneider, Sophia Grahl, Audrey P Fan, Christine Tardif, Arno Villringer, Pierre‐Louis Bazin, Christopher J Steele, Claudine J Gauthier

Human Brain Mapping 44 (14), 4938-4955 · 01 Jan 2023

Multivariate white matter differences links to cognition in individuals with family history of Alzheimer’s disease and APOE4 genetic risk

Stefanie A Tremblay, R. Nathan Spreng, Zaki Alasmar, Amir Pirhadi, Christine L Tardif, …, Ilana R Leppert, Felix Carbonell, Yasser Iturria Medina, Christopher J Steele, Claudine J Gauthier

Alzheimer's & Dementia 19, e081953 · 01 Jan 2023

2021

The role of cerebrovascular-reactivity mapping in functional MRI: calibrated fMRI and resting-state fMRI

JJ Chen, CJ Gauthier

Frontiers in physiology 12, 657362 · 01 Jan 2021

White matter microstructural changes in short-term learning of a continuous visuomotor sequence

Stéfanie A. Tremblay, Anna-Thekla Jäger, Julia Huck, Chiara Giacosa, Stephanie Beram, …, Arno Villringer, Christine L. Tardif, Pierre-Louis Bazin, Christopher J. Steele, Claudine J. Gauthier

Brain Structure and Function 226 (6), 1677-1698 · 01 Jan 2021

Sex moderations in the relationship between aortic stiffness, cognition, and cerebrovascular reactivity in healthy older adults

Dalia Sabra, Brittany Intzandt, Laurence Desjardins-Crepeau, Antoine Langeard, Christopher J. Steele, Frédérique Frouin, Richard D. Hoge, Louis Bherer, Claudine J. Gauthier

PLoS One 16 (9), e0257815 · 01 Jan 2021

2020

$Elevated brain oxygen extraction fraction measured by MRI susceptibility relates to perfusion status in acute ischemic stroke$

Elevated brain oxygen extraction fraction measured by MRI susceptibility relates to perfusion status in acute ischemic stroke

Audrey P Fan, Ahmed A Khalil, Jochen B Fiebach, Greg Zaharchuk, Arno Villringer, Kersten Villringer, Claudine J Gauthier

Journal of Cerebral Blood Flow & Metabolism 40 (3), 539-551 · 01 Jan 2020

Higher cardiovascular fitness level is associated with lower cerebrovascular reactivity and perfusion in healthy older adults

Brittany Intzandt, Dalia Sabra, Catherine Foster, Laurence Desjardins-Crépeau, Richard D Hoge, Christopher J Steele, Louis Bherer, Claudine J Gauthier

Journal of Cerebral Blood Flow & Metabolism 40 (7), 1468-1481 · 01 Jan 2020

2019

BOLD signal physiology: models and applications

CJ Gauthier, AP Fan

Neuroimage 187, 116-127 · 01 Jan 2019

Neurovascular Coupling

C Gauthier

International Society for Magnetic Resonance in Medicine 27th Annual Meeting … · 01 Jan 2019

Ventilatory outcomes during a VO2max test are related to measures of cerebral vascular health in aging

CJ Gauthier

6th Annual PERFORM Centre Research Conference · 01 Jan 2019

The influence of draining veins on apparent grey matter volume changes caused by hypercapnia

Julia Huck, Christopher Steele, Anna-Thekla Jäger, Audrey Fan, Sophia Grahl, Christine Tardif, Uta Schneider, Arno Villringer, Pierre-Louis Bazin, Claudine Gauthier

ISMRM 27th Annual Meeting and Exhibition · 01 Jan 2019

Arterial stiffness and brain integrity: A review of MRI findings

A Badji, D Sabra, L Bherer, J Cohen-Adad, H Girouard, CJ Gauthier

Ageing research reviews 53, 100907 · 01 Jan 2019

High resolution atlas of the venous brain vasculature from 7 T quantitative susceptibility maps

Julia Huck, Yvonne Wanner, Audrey P. Fan, Anna-Thekla Jäger, Sophia Grahl, …, Arno Villringer, Christopher J. Steele, Christine L. Tardif, Pierre-Louis Bazin, Claudine J. Gauthier

Brain Structure and Function 224 (7), 2467-2485 · 01 Jan 2019

2018

High resolution atlasing of the venous brain vasculature from 7T quantitative susceptibility

Julia Huck, Yvonne Wanner, Audrey P Fan, Anna-Thekla Schmidt, Sophia Grahl, …, Arno Villringer, Christopher J Steele, Christine L Tardif, Pierre-Louis Bazin, Claudine J Gauthier

bioRxiv 444349 · 01 Jan 2018

Functional and Metabolic MRI

CJ Gauthier, AP Fan

Quantitative MRI of the Brain. Principles of Physical Measurement, 2nd edn … · 01 Jan 2018

Enhanced fitness relates to reduced cerebrovascular reactivity and perfusion in a sample of very healthy older adults

Brittany Intzandt, Dalia Sabra, Catherine Foster, Laurence Desjardins-Crépeau, Rick Hoge, Christopher J Steele, Louis Bherer, Claudine J Gauthier

bioRxiv, 444208 · 01 Jan 2018

2017

Investigation of the confounding effects of vasculature and metabolism on computational anatomy studies

C.L. Tardif, C.J. Steele, L. Lampe, P.-L. Bazin, P. Ragert, A. Villringer, C.J. Gauthier

Neuroimage 149, 233-243 · 01 Jan 2017

Age differences in brain signal variability are robust to multiple vascular controls

DD Garrett, U Lindenberger, RD Hoge, CJ Gauthier

Scientific reports 7 (1), 10149 · 01 Jan 2017

2016

Baseline oxygenation in the brain: correlation between respiratory-calibration and susceptibility methods

Audrey P. Fan, Andreas Schäfer, Laurentius Huber, Leonie Lampe, Steffen von Smuda, Harald E. Möller, Arno Villringer, Claudine J. Gauthier

Neuroimage 125, 920-931 · 01 Jan 2016

Vessel segmentation from quantitative susceptibility maps for local oxygenation venography

PL Bazin, V Plessis, AP Fan, A Villringer, CJ Gauthier

2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI), 1135-1138 · 01 Jan 2016

2015

Hearts and minds: linking vascular rigidity and aerobic fitness with cognitive aging

CJ Gauthier, M Lefort, S Mekary, L Desjardins-Crépeau, A Skimminge

Neurobiology of aging 36 (1), 304-314 · 01 Jan 2015

Automated vessel segmentation from quantitative susceptibility maps at 7 Tesla

Pierre-Louis Bazin, AP Fan, Gabriela Mianowska, Agnieska Olbrich, Andreas Schäfer, Arno Villringer, CJ Gauthier

Proceedings of the Twenty-forth Annual Meeting of the ISMRM,(Toronto, ON) 2287 · 01 Jan 2015

Baseline oxygenation in the brain: Correlation with BOLD and comparison between susceptibility and respiratory-calibration methods

Audrey P Fan, Andreas Schaefer, Laurentius Huber, Steffen N Krieger, Harald E Moeller, Arno Villringer, Claudine J Gauthier

23rd Annual Meeting of the International Society for Magnetic Resonance in … · 01 Jan 2015

2014

Using carbogen for calibrated fMRI at 7 Tesla: Comparison of direct and modelled estimation of the M parameter

Steffen N. Krieger, Dimo Ivanov, Laurentius Huber, Elisabeth Roggenhofer, Bernhard Sehm, Robert Turner, Gary F. Egan, Claudine J. Gauthier

Neuroimage 84, 605-614 · 01 Jan 2014

Comparison of absolute brain oxygenation in visual cortex by Quantitative O2 imaging (QUO2) and susceptibility MRI

A Fan, A Schafer, L Huber, S Krieger, HE Möller, A Villringer, C Gauthier

Leipzig Symposium: Imaging Cerebral Physiology · 01 Jan 2014

2013

A generalized procedure for calibrated MRI incorporating hyperoxia and hypercapnia

CJ Gauthier, RD Hoge

Human brain mapping 34 (5), 1053-1069 · 01 Jan 2013

Age dependence of hemodynamic response characteristics in human functional magnetic resonance imaging

CJ Gauthier, C Madjar, L Desjardins-Crépeau, P Bellec, L Bherer

Neurobiology of aging 34 (5), 1469-1485 · 01 Jan 2013

2012

Quantitative functional neuroimaging of cerebral physiology in healthy aging

C Gauthier

[no publisher info] · 01 Jan 2012

Magnetic resonance imaging of resting OEF and CMRO2 using a generalized calibration model for hypercapnia and hyperoxia

CJ Gauthier, RD Hoge

Neuroimage 60 (2), 1212-1225 · 01 Jan 2012

Absolute quantification of resting oxygen metabolism and metabolic reactivity during functional activation using QUO2 MRI

CJ Gauthier, L Desjardins-Crépeau, C Madjar, L Bherer, RD Hoge

Neuroimage 63 (3), 1353-1363 · 01 Jan 2012

2011

Elimination of visually evoked BOLD responses during carbogen inhalation: implications for calibrated MRI

CJ Gauthier, C Madjar, FB Tancredi, B Stefanovic, RD Hoge

Neuroimage 54 (2), 1001-1011 · 01 Jan 2011

2010

Saturation of visually evoked BOLD response during carbogen inhalation

CJ Gauthier, C Madjar, RD Hoge

Proc. Intl. Soc. Mag. Reson. Med 18, 1133 · 01 Jan 2010

2009

Investigation of venous effects in spinal cord fMRI using hypercapnia

C Gauthier, J Cohen-Adad, J Brooks, S Rossignol, RD Hoge

Proceedings 17th Scientific Meeting. International Society for Magnetic … · 01 Jan 2009

Test-Retest Reliability Assessment for Longitudinal Studies Spanning a Major MRI System Upgrade

C Gauthier, C Madjar, O Monchi, J Doyon, RD Hoge

Proc. Intl. Soc. Mag. Reson. Med 17, 3732 · 01 Jan 2009

2008

BOLD‐Perfusion Coupling during Monocular and Binocular Stimulation

C Gauthier, RD Hoge

International Journal of Biomedical Imaging 2008 (1), 628718 · 01 Jan 2008

Richard D. Hoge Co-Investigator Contacts

CJ Gauthier